Thanks for all of the suggestions guys, most of which I've already tried. I know I'm not the first to experience this. Actually, the knot tying isn't really a problem as long as I tie it big (how I practice with eyes closed anyway). I finally found a 4X pair of magnifiers that helped. I'm going to try the magnetic threader which I just bought. I also had a brainstorm and stopped in a fabric store today and bought some needle threaders. Thanks again, keep the hints and ideas coming. I'll try to provide information later on the needle threaders and my experience with the magnetic threader.
Have any of you tried this: