Originally Posted by wt bash
Anywhere between Potter and Tioga Counties, South all the way to the border of Maryland. The center of Pennsylvania is chock full of trout water and some of the most beautiful country East of the Mississippi. You can cherry pick the entire region via 81 and hit some famous, some unheard of, and some pristine wild trout waters all in the same time span it takes me to drive to mediocre trout water in Ohio.
That's a beautiful part of the state, loaded with options of some incredible fishing, as you well know. Big water, medium water, famous water, small streams and unknowns are pretty much all within a 2:00-2:30 window. Steelies or Salmon are a bit of a push further at 4:00-5:00.
Not sure what your occupation is, but as you're likely finding jobs can be limited. State College/Lock Haven put you at the center of the most variety of options I'd think. There's always the old stomping grounds of the master himself, Ard which is Williamsport.
Good luck on the new accommodations and job.