From my experience color doesn't seem to make too much difference. Where I fish there is never really a hatch of one species. Usually a mix of different species in any one moment.
I fish a size 14 - 18 fly, sometimes going up to size 10. Try to keep my rod tip up with a high visibility sighter and impart some action when needed. To see what the fish see can spark some creativity. The first time it's a happy accident. Afterwards it's become a part of your repertoire.