Re: Moose River Plains or ?
From Syracuse I would go right up 81 north until I reached Rt. 3; this runs with Rt 126 east and then breaks off into Rt 3.
This road (I haven't rode it since 1988) will thread across the state taking you through the Indian River valley and on to Tupper & Cranberry Lakes area. Lots to see in these little villages. There are numerous streams that run along and cross Rt 3 and some nice camp grounds as you head east/north east on the road.
Rt 3 will go right to Saranac Lake and Lake Placid is just south of there. The road south out of the town of Lake Placid goes through some pretty country but my last ride up there I took Rt 9 over the I-87 known as The Northway and then cruised down the Northway to Lake George. Historic sites include Lake George and Ticonderoga. Of course L. Placid was the 1980 Olympic spot and is very much developed since then but a great place to grab lunch and the T shirt............
Hope you have enough time to take this area in, I made several runs up there while I lived in northern Pennsylvania and wish I had done more.