There are places that you may have shots at Bonefish between Isla Blanca and Isla Holbox, but you may have better shots at baby Tarpon or snook.
I do not know the guide services out of Isla Blanca, but there are some. From my understanding, they will pick you up from your hotel.
As for fly lines, you can get Sage Equator Taper
lines off eBay at reduced prices. It is a great all around tropical line that can throw sparse Bonefish flies, as well as, larger baby Tarpon flies.
Enjoy your trip.