What he said/ CDC Sulphurs is the name of the game. When there's no dry activity try pheasant tails, sulphur split cases, and zebra midges (black, white, anything goes - size 18-22).
Terrestrials along high grassy areas - hoppers, beatles, ants.
Be prepared to have company. Me included. It's gotten crazy w/ people but there's so may fish, if you move away from the crowds, there's still fish to be had. Start at the weir damn and work your way down. I think there's 12 miles to the lake.....
The South Holston Fly Shop is a must stop while there. Rod and Matt are good peeps. Tons of techniques, flys and setup help. Full service fly shop and guide service
I wish my name was Rod Champion - Jealous?
Check the water release schedule. If you don't it's nearly impossible to fish on high water. TVA: South Holston
Be sneaky, use small indicators, and wait for the major hatch. It will happen!!! Fish nymphs in the rapids and hold on. The water is low in spots, but if you move around it's fabulous.
I struggled for a year, but I can say now it's fish on every trip.
Let me know if you want some company.